What has to be the best characteristics of vitamin supplements that fight or prevent acne? You want a supplement that will contain vitamin A, fish oil and other ingredients that will stop acne and the sub-skin levels. This way the acne can not proliferate on the surface of the skin. The bacteria-producing acne must be killed to stop acne in its tracks. These ingredients must be able to maintain extensive anti-inflammatory properties to prevent inflammation from appearing on the skin. One expert says the core culprit of acne is when the skin and the levels below the skin become inflamed.