Isagenix Reviews: Is All the Hype Real?

(Last Updated On: August 3, 2018)

Well is it a hype or can Isagenix produce all the fabulous results we see reported everywhere on the internet? Could it be the hype of the century? Are you wasting your money purchasing this wonder formula? Is it safe to digest? These are just some of the questions people are asking the world over. Those people who are looking to get and stay healthy. We wonder should Isagenix be apart  of a healthy lifestyle? We want healthy elements in our diets not ones that will cause us health problems.

What about this Isagenix

Let’s travel back in time to around 2002 when Isagenix first put this product on the market. They have been in business for almost 14 years. They have a good rating with the BBB which is always a good sign that the company will deal with customers in good faith. Isagenix is a supplement company that offers weight-loss solutions. The products advertise that they contain all natural products which is commendable but it still doesn’t mean there couldn’t be negative side effects. There products have ample clinical support to justify their claims. None of their cleansing products contain any laxatives which is good. The price of the protein shake is out of this world though. They want $350.00 for a weight loss program. Some think the price is fair because that is the typical price for protein shakes on the current market. Others say it is too high of a price for a product that tasted terrible. Even if the product works well it doesn’t justify the high price tag.

The company’s website doesn’t support the product with any clinical support  of its validity to help people lose weight. There has been scientific proof that validates that Isagenix can help dieters lose weight with their product’s active ingredients.

Some Reviews

  • One customer said that the product tasted horrific and made the consumer feel nasty. The product absolutely did nothing for this person and they thought the price was way too high. There was other issues they didn’t elaborate on.
  • One customer said the product worked great and made the consumer feel really great and they were able to lose weight.
  • Another dieter said a small jar for a high price.
  • One other consumer said great price and great product.

These reviews are mixed at best and they fall on opposite ends of the spectrum. One side says product works great and is the best thing they have come across. The other side says it tastes horrific and didn’t do a thing for them. So what are you supposed to do with these polarizing viewpoints. We need to dig a little deeper and investigate other reviews and get some medical opinions on the product. Could it be the product just worked differently on each person’s metabolism? Or is it just a plain old case that the product is ineffective to help with weight loss?

Further Investigation from a Medical Perspective

Isagenix, is a combination of products that are used in different combinations that are used for detoxification,  natural cleansing, and supplementation to help with weight loss. It’s also supposed to increase energy levels and performance. It is an agent for healthy aging. The reviewer further states that the product is able to burn fat while supporting lean muscle, maintains cholesterol levels, support telomeres, (inside the nucleus of a human cell the genes are arranged along twisted double-stranded molecules of DNA called chromosomes. On the end of these chromosomes are stretches of DNA called telomeres which protect the genetic data, help cells divide, and hold the secrets to why we age and get cancer.) improves resistance to illness, improves cravings, increases body composition , and slows aging.The concern of this doctor was that there is no clinically proven testing to support that this product is beneficial in helping consumers lose weight. Also, there is no scientific evidence to support the other benefits of the drug above.

But an e-mail correspondent notified her that clinical tests were in progress which were funded by Isagenix. She asked the source to notify her when the results were in from the studies. The studies were completed and published online.  They were published in the journal Nutrition and Metabolism (and the authors according to this doctor  had to pay $1805 to have the results published in the journal) and the full study results can be found online. The studies were done by medical peers and she said they did a poor job in conducting the tests and analyzing the results.

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(The full study can be found at this link.) A couple of disturbing trends surface from these studies:Isagenix funded the studies so how objective were the results and the publishers had to pay $1805 to have it published in the medical journal mentioned above. For a more objective results a third party could have funded this project. Was there any conflict of interest with the researchers? They were employed and paid by Isagenix.

Here is basically the criterion the researchers based their study on:

  • Obese women aged 35-65 who have no current battles with diabetes. Their weight should have been staple the previous three months of the study. They were broken into two groups.
  • There were no men of any age chosen in the experimental group and there were no young women overweight but not obese selected.
  • The researchers divided the groups into two sub-groups. One would be on a restricted calorie diet.For two  meals a day the group would consume a liquid diet replacement meal. ( Isalean shakes which is only one component of the Isagenix system)
  • The other group would consume the same amount of calories provided for by regular food.
  • Intermittent fasting (one day a week) was added to the equation because it is a popular trend that is growing. (The weakness here is intermittent fasting is not part of the Isagenix weight loss system.
  • The study was conducted for ten weeks (Note:The researchers pointed out another weakness in the study. The groups were allowed to pick their own foods after instruction by the dietician. The food choices weren’t controlled by the researchers.)
  • Breakfast and lunch was limited to 240 calories each and dinner to 400-600 calories
  • 35% of the calories  were from fats and 50-60% of the calories were from carbohydrates
  • The consumers would talk via telephone and they would recall what they ate the previous 24 hours

The Results


Honestly the results were positive but by no means were they world changing. The control group ,drinking the Isalean shakes, over 8 weeks lost 1.1 lbs. And the group eating regular foods lost 0.8 lbs. Which isn’t a major difference between the two groups. The protein shake group reduced their daily calorie intake from 1708 to 1255. The other group reduced their calorie intake by less than 500 calories a day. Naturally, they lost less weight than the shake group. The doctor who wrote this review calculated that losing 500 calories a day should result in a weight loss of 1 lb. per week. Without any need for fasting, meal replacement or supplements. As can be seen over the 8 week period neither group reached this 1 lb threshold.

So, if on a regular food diet the person reduces their calorie  intake by 500 calories (with no extra dieting aides)  is supposed to lose 1 lb. per week. Then a person drinking the protein shakes should reflect even a greater weight loss average per week.

But according to the study the shake group lost an average of about ½ lb. per week. So this may reflect the weakness of the Isagenix shakes being a beneficial weight loss option. The doctor also noted the numbers could have been skewed because the researchers were being paid by Isagenix. Also, the head researcher had direct links to the company. This could make for serious conflict of interest matters.

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Oh Boy the Numbers

The review further reported that some of the final numbers didn’t add up. For instance, the total calorie intake for the Isalean group at week 10 was 1255. But if you add the numbers from table 2 for the calories intake from fat, protein, and carbohydrates the numbers add p to 1655. Similarly, if you look at the total calorie intake at week 10 for the regular food group you will find another discrepancy. Table 2 reports that the group calorie intake was 1444 but if you add up the calories from the fat, protein, and carbohydrates the total is 1279. The doctor asked the team representative about the inconsistencies. The answer was the team did notice these inconsistencies in the numbers. But the reason for this error was unclear as reported by the lead investigator.

There were more discrepancies with the numbers. The Isalean group reportedly received 240 calories from each of the two shakes consumed. They also ate a dinner containing 400-600 calories. This should add up to between 880 to 1080 calories not the 1255 reported. The regular food group was supposed to consume the exact amount of calories as the Isalean group not th 1444 reported. The doctor of the review finally gave up trying to figure out why the numbers didn’t add up.

The researchers concluded that the combination of intermittent fasting coupled with calorie reduction plus liquid replacement shakes (Isagenix product) is beneficial in losing weight. The doctor, in the review, concluded that the results couldn’t be interpreted correctly and that the Isagenix weight loss system was no more effective in causing weight loss than any other diet supplementary program.

The numbers being misrepresented in the study plus the difficulty in making sense of the results of the study point to that Isagenix may not be such an effective weight loss option. Another issue is the team couldn’t account why the numbers were off. Their interpretation of the final results weren’t clear either to say the least. This seems to be the only clinical evidence to support the benefits of using Isagenix products as weight loss agents. Unfortunately, the numbers weren’t clear and some of the factors the study was based on are irrelevant to the core of the Isagenix weight loss system.   

The Emperor’s Clothes

What in the world does the story of the emperor’s clothes have to do with Isagenix reviews? Well it’s like this Everyone is afraid  to expose what Isagenix is all about because they don’t want to look foolish. Like the crowd in the emperor’s story no one wanted to look foolish and tell the king he had no clothes on.

Another Medical Review

Reasons  why Isagenix doesn’t live up to its claims of weight loss:

  • Proponents of Isagenix say you can lose up to 15 lbs. in 9 days through a  “cleanse” from using Isagenix. Generally anytime you cleanse your bowels or empty them you will lose weight. You can lose 3 or 4 lbs by not eating for one day. The liver uses a backup energy system where glucose is combined with water. The body then burns the glucose and you end up urinating 4 times more water than the glucose your body has burned. So, you will lose the weight anyway through natural means and the Isagenix really isn’t needed to be consumed to cleanse the body to lose weight. Don’t eat for one day and the body will naturally lose the weight
  • Isagenix contains fructose in a lot of its products. A limited amount of fructose activates a metabolic pathway into the liver. This helps the liver get rid of high levels of glucose which would otherwise be stored as fat in the body. This would result in weight gain. You would have to be on a high-carb diet for this to happen. So if you were on a high-carb diet then you could take Isagenix to help breakdown the excess glucose from all the carbohydrates you would be consuming. Then you would lose weight. But why be on a high-carb diet in the first place?  You don’t eat a lot of carbohydrates you won’t need to consume Isagenix products.
  • Gluten is a main ingredient in a lot of their products. Gluten isn’t the culprit many people think it is. But if you really cannot consume gluten then you shouldn’t be using Isagenix
  • Isagenix also uses peanuts in large quantities in their products. Peanut allergies are a common occurrence in America. Peanut allergies can be deadly so why use Isagenix products if you will develop peanut allergies that could really hurt you health wise?
  • Isagenix is multi-level marketing program. So friends will pressure friends to buy this product they don’t need. So a profit can be made. Some of the reasons they state to buy the product are: “Our foods lack essential nutrients because of depleted soils.” This simply isn’t true the animals and plants we eat have grown from nutrients they extracted from the soil. Another quote” Our bodies aren’t set up to detoxify modern foods.”  Really, the liver is quite capable of detoxifying food and will even retoxify food when it needs to. Isagenix actually contains chemicals that burden the liver and prevent it from naturally detoxify food.
  • The isagenix program is set up so you  intake two replacement meals (drink their protein shakes) and eat one low carb meal then you lose weight. You can eat two chocolate sundaes and eat one low carb meal and lose weight. You don’t need to consume Isagenix products to lose weight. If you decrease  your consumption of regular food you will lose weight.

The Final Summary

In light of our previous discussion it seems like the hype many favorable Isagenix reviews state are founded on non-scientific data. A lot of the claims made by Isagenix distributors say as to why you need to buy the product simply aren’t true. The Isagenix website reportedly doesn’t make any reference to the only clinical study conducted on their product. The clinical study was funded by the company. In the review, referenced earlier in this article it was found the final numbers didn’t add up. Also the study was based on intermittent fasting which isn’t apart of the Isagenix weight loss system.

The study was financed by the company and the lead researcher had direct links to Isagenix which could have led to some serious conflict of interest issues. The results could have been skewed in favor of the company. The tam couldn’t really give a solid answer as to why the numbers didn’t match up.This brings into the question of the integrity of the study. Also, the case samples of people who were selected to participate in the studies were limited. This could have colored the results as well. Based on other medical reviews Isagenix really isn’t necessary to consume to lose weight.

People can lose weight just by minimizing how much regular food they eat on a daily basis. This way they can save $350 dollars on a dietary program that really doesn’t work anyway. Referencing the clinical study again, the two groups did lose weight and the Isagenix group slightly lost more weight than the other control group. But the increase was so minor it wasn’t worth consuming the Isagenix product in the first place. The product just doesn’t seem to be very effective in helping people to lose weight.    

Written by Irina Radosevic MD
Irina graduated from the University of Belgrade, School of Medicine as a Doctor of Medicine (MD) and spent over 3 years working in the Clinical Hospital Center Zvezdara, in the Department of Emergency Medicine. She also undertook a postgraduate in Cardiology from the same University and had previously worked for over a year as a Physician and Nutritionist Dietitian for the Fitness club Green Zone. She eventually left her chaotic but fulfilling job in the ER to pursue her passion of writing, travelling and mountain climbing which has included writing a first aid course for the alpine club of Belgrade. Irina currently works as a VA for PintMedia focusing on medical and travel writing. Feel free to connect with Irina on LinkedIn and FaceBook. Her CV can be seen here.